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You should replace your diffuser every 6 months, and replace your refill every month.  Make sure to follow the instructions when plugging in your diffuser - you need to make sure it is plugged in right side up (see examples in the images below).  \n\nTry not to plug the diffuser under items (e.g. shelves) or close to objects (e.g. behind curtain or doors) as this affects efficacy.  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It is safe to double in times of increased stress.\u003c\/p\u003e\n\u003ch3\u003eSafety Information\u003c\/h3\u003e\u003cp\u003eCAUTION: Safe use in pregnant animals or animals intended for breeding has not been proven.\n\nCAUTION: If animal’s condition worsens or does not improve, stop product administration and consult your veterinarian.\n\nWARNING: Not for human consumption.\u003c\/p\u003e","brand":"VetriScience","offers":[{"title":"Dogs \/ 60 chews","offer_id":51853067419879,"sku":"vc-1341-3185-7637","price":36.04,"currency_code":"USD","in_stock":true},{"title":"Cats \/ 45 chews","offer_id":51858947014887,"sku":"vc-1341-5867-12157","price":21.94,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0698\/4387\/8119\/files\/100453-11_dcbc5f64-e52d-4ce6-b417-ee012f922cee.webp?v=1774103822"},{"product_id":"vc-1490","title":"Feliway Classic","description":"\u003cp\u003eSends \"happy messages\" to cats to help them feel secure while traveling, at the vet, or at home.\u003c\/p\u003e","brand":"Feliway® Classic","offers":[{"title":"30 Day Refill \/ 48mL bottle","offer_id":51853074333927,"sku":"vc-1490-3419-7942","price":30.0,"currency_code":"USD","in_stock":true},{"title":"30 Day Starter Kit \/ Plug-in and 30 Day Refill","offer_id":51855026520295,"sku":"vc-1490-3420-7943","price":34.79,"currency_code":"USD","in_stock":true},{"title":"Calming Spray \/ 20mL bottle","offer_id":51855026553063,"sku":"vc-1490-3421-7944","price":24.29,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0698\/4387\/8119\/files\/100768-425_a85cb631-b029-4611-aefb-465383caa3cd.webp?v=1774103832"},{"product_id":"vc-1493","title":"Feliway MultiCat","description":"\u003cp\u003eHelps reduce the common signs of tension and conflict between cats at home.\u003c\/p\u003e","brand":"Feliway®","offers":[{"title":"30 Day Refill \/ 48mL bottle","offer_id":51853074399463,"sku":"vc-1493-3422-7945","price":30.0,"currency_code":"USD","in_stock":true},{"title":"30 Day Starter Kit \/ Plug-in and 30 Day Refill","offer_id":51855026585831,"sku":"vc-1493-3423-7946","price":34.79,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0698\/4387\/8119\/files\/100764-1.webp?v=1774103834"},{"product_id":"vc-1495","title":"Feliway Optimum","description":"\u003cp\u003eFELIWAY® Optimum functions by releasing calming messages within the household, promoting increased serenity for cats.\u003c\/p\u003e","brand":"Feliway® Optimum","offers":[{"title":"30 Day Refill \/ 48mL bottle","offer_id":51853074432231,"sku":"vc-1495-3424-7947","price":34.2,"currency_code":"USD","in_stock":true},{"title":"30 Day Starter Kit \/ Plug-in and 30 Day Refill","offer_id":51855026618599,"sku":"vc-1495-3425-7948","price":38.87,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0698\/4387\/8119\/files\/100766-1.png?v=1774103828"},{"product_id":"vc-1508","title":"Fluoxetine HCl Capsule","description":"\u003cp\u003eFluoxetine is a selective serotonin reuptake inhibitor (SSRI) used in dogs and cats for the long-term management of behavioral disorders rooted in anxiety and reactivity. The veterinary brand Reconcile is FDA-approved for canine separation anxiety, and generic fluoxetine is also widely prescribed off-label for fear-based aggression, urine marking in cats, compulsive behaviors (tail chasing, lick granuloma, over-grooming), and storm phobia. Fluoxetine works by increasing the availability of serotonin in the brain, helping the patient stay below the threshold where reactive behaviors take over.\u003c\/p\u003e\n\u003ch3\u003eWhat fluoxetine is used for\u003c\/h3\u003e\n\u003cp\u003eCommon indications include canine separation anxiety (panic when left alone, destructive chewing, vocalization, indoor accidents despite house-training), generalized anxiety, fear-based reactivity toward people or other dogs, noise phobia, compulsive disorders, and feline house-soiling and urine marking. Fluoxetine is intended to be paired with a behavior-modification plan from your veterinarian or a board-certified veterinary behaviorist — medication alone rarely solves a behavior problem.\u003c\/p\u003e\n\u003ch3\u003eImportant considerations\u003c\/h3\u003e\n\u003cp\u003eFluoxetine is a daily medication and takes 4–8 weeks to reach full effect — owners often see only subtle changes in the first 2 weeks. Common early side effects include reduced appetite, lethargy, and mild GI upset, which usually resolve within the first 1–2 weeks. Less common effects include irritability, restlessness, or new-onset aggression — if your pet seems worse after starting fluoxetine, contact your veterinarian. Do not combine fluoxetine with other serotonergic drugs (trazodone, tramadol, MAOIs, selegiline) without veterinary direction; the combination can rarely cause serotonin syndrome. Do not stop fluoxetine abruptly after long-term use — taper under guidance.\u003c\/p\u003e\n\u003cp\u003eSmarty Vets dispenses Reconcile chewable tablets and generic fluoxetine capsules and tablets, plus pharmacy-compounded liquids for cats and small dogs, all with a valid veterinary prescription.\u003c\/p\u003e\n\u003cp\u003eClick \u003cstrong\u003eBuy on VetCove\u003c\/strong\u003e to order.\u003c\/p\u003e","brand":"Fluoxetine","offers":[{"title":"10mg \/ 1 capsule","offer_id":51853074530535,"sku":"vc-1508-3444-7968","price":0.09,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 20 capsules","offer_id":51855026716903,"sku":"vc-1508-3444-12296","price":11.53,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 30 capsules","offer_id":51855026749671,"sku":"vc-1508-3444-12297","price":11.87,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 60 capsules","offer_id":51855026782439,"sku":"vc-1508-3444-12298","price":12.87,"currency_code":"USD","in_stock":true},{"title":"10mg \/ 100 capsules","offer_id":51855026815207,"sku":"vc-1508-3444-7969","price":14.2,"currency_code":"USD","in_stock":true},{"title":"20mg \/ 1 capsule","offer_id":51855026847975,"sku":"vc-1508-3445-7970","price":0.1,"currency_code":"USD","in_stock":true},{"title":"20mg \/ 20 capsules","offer_id":51855026880743,"sku":"vc-1508-3445-12299","price":11.31,"currency_code":"USD","in_stock":true},{"title":"20mg \/ 30 capsules","offer_id":51855026913511,"sku":"vc-1508-3445-12300","price":11.53,"currency_code":"USD","in_stock":true},{"title":"20mg \/ 60 capsules","offer_id":51855026946279,"sku":"vc-1508-3445-12301","price":12.2,"currency_code":"USD","in_stock":true},{"title":"20mg \/ 100 capsules","offer_id":51855026979047,"sku":"vc-1508-3445-7971","price":13.09,"currency_code":"USD","in_stock":true},{"title":"40mg \/ 1 capsule","offer_id":51855027011815,"sku":"vc-1508-3446-7972","price":0.21,"currency_code":"USD","in_stock":true},{"title":"40mg \/ 30 capsules","offer_id":51855027044583,"sku":"vc-1508-3446-7973","price":12.2,"currency_code":"USD","in_stock":true},{"title":"40mg \/ 90 capsules","offer_id":51855027077351,"sku":"vc-1508-3446-14291","price":18.9,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0698\/4387\/8119\/files\/100790-3651.webp?v=1774103812"},{"product_id":"vc-1509","title":"Fluoxetine Oral Solution","description":"\u003cp\u003eFluoxetine is a selective serotonin reuptake inhibitor (SSRI) used in dogs and cats for the long-term management of behavioral disorders rooted in anxiety and reactivity. 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You simply put the collar on your dog - you'll want to tighten the collar snugly so it fits against your dog's body, but you want it loose enough so you can slide one to two fingers underneath.  Once you've attached the collar, you can trim off the excess at the end of the collar.  \n\nThunderEase® Calming Collar is activated by your dog's body heat, so it must remain in contact with your dog's skin in order to release the calming pheromones.  We recommend that you keep the collar on your dog at all times, except when bathed or exposed to significant amounts of water (ie: going swimming).  The collar will stop diffusing if wet, however it will begin working again once it is dry!   \n\nOne ThunderEase® collar lasts up to 30 days, so you should replace your collar every 4 weeks for the maximum calm for your pet.  Most pet parents will begin to see results within 7 days!\n\nNote: The ThunderEase® Calming Collar is meant to be worn in conjunction with a normal collar.  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